Here's another thing we can and do give our children that like E is
also an anti-oxidant. These studies are of course in animals -not
people...but for ethical reasons -such as in the case of the last
study I posted about toxins passing the placenta- that's the only way.
Also the following speaks about DHA -but I believe it was momresearch
who just posted about Dr. AJ Richardson and she is the one that
taught me about the importance of the other Omega 3 -EPA at the First
Apraxia Conference back in 2001. http://www.cherab.
(and many of us found this out ourselves)
J. Nutr. 135:549-555, March 2005
Nutritional Neurosciences
Chronic Administration of Docosahexaenoic Acid
Ameliorates the Impairment of Spatial Cognition
Learning Ability in Amyloid ß-Infused Rats
Michio Hashimoto*,1, Yoko Tanabe*,{dagger}
Fujii*, Toshihiko Kikuta**, Hitoshi Shibata** and
Osamu Shido*
* Department of Environmental Physiology, {dagger}
Center for Integrated Research in Science, Shimane
University Faculty of Medicine, Izumo 693-8501, Japan
and ** Department of Life Science and Biotechnology,
Shimane University of Faculty of Life and
Environmental Science, Matsue 690-8504, Japan
1To whom correspondence should be addressed. E-mail:
michio1@med.
ABSTRACT
TOP
ABSTRACT
MATERIALS AND METHODS
RESULTS
DISCUSSION
LITERATURE CITED
We investigated whether administration of
docosahexaenoic acid (DHA), a major (n-3) fatty acid
of the brain, ameliorates the impairment of learning
ability in an animal model of Alzheimer's disease
(AD), rats infused with amyloid-ß (Aß) peptide (1-40)
into the cerebral ventricle. Inbred 3rd generation
male rats (20 wk old) fed a fish oil-deficient diet
were randomly divided into 4 groups: a vehicle group,
an Aß peptide-infused group (Aß group), a DHA group,
and an Aß + DHA group. A mini-osmotic pump filled with
Aß peptide or vehicle was implanted in the rats, and
they were tested for learning ability-related
reference and working memory in an 8-arm radial maze.
The rats were then orally fed DHA dissolved in 5% gum
Arabic solution at 300 mg/(kg · d) (DHA and Aß + DHA
groups) or vehicle alone (vehicle and Aß groups) and
tested again for learning ability. DHA administered
for 12 wk significantly reduced the increase in the
number of reference and working memory errors in the
Aß-infused rats, and increased both the
cortico-hippocampal level of DHA and the molar ratio
of DHA/arachidonic acid, suggesting an amelioration of
the impaired spatial cognition learning ability.
Furthermore, DHA suppressed the increases in the
levels of lipid peroxide and reactive oxygen species
in the cerebral cortex and the hippocampus of
Aß-infused rats, suggesting that DHA increases
antioxidative defenses. DHA is thus a possible
therapeutic agent for ameliorating learning
deficiencies due to Alzheimer's disease.
=====
Lisa Geng
President CHERAB Foundation
Communication Help, Education, Research, Apraxia Base
http://www.cherab.
Co Founder Speechville
The Pink Mission
http://www.thepinkm
772-335-5135
"Help give our cherubs a smile and a voice"
--- In childrensapraxianet
<annedevlinhoag@
>
> Anyone try vitamin C ? I was telling my Dad about Vitamin E, and he
> was saying that vitamin C also had antioxidant properties, and maybe
> we should try that too ? Just wondering if anyone had thought or
> discussed on vitamin C ? Thanks y'all..
>
> Annie
>
New book on late talking! http://www.speechville.com/late.talker.html
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